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Natural Product Chemistry Research Brief

大枫子油:驱避与修复的双重作用机制

Chaulmoogra Oil: Dual Mechanisms of Repellency and Post-Bite Repair

本研究聚焦大枫子油中独特的环戊烯基脂肪酸 (CPFAs)。不同于传统易挥发驱蚊剂,它在皮肤表面形成持久的触觉防护屏障,并能调控叮咬后的局部皮肤组织修复。
This study focuses on the unique Cyclopentenyl Fatty Acids (CPFAs) in Chaulmoogra Oil. Unlike volatile repellents, it forms a long-lasting tactile barrier on the skin and modulates post-bite epidermal repair.

御本堂® 大枫子油 加拿大 NPN: 80091348 祛风除湿 · 润肤止痒
Product Info / 产品信息

御本堂® 大枫子油

YUBENTANG DAFENGZI YOU

NPN 80091348
规格 / Specification:
15 ml / 瓶 (15 ml / Bottle)
功能主治 / Indications & Functions:
祛风除湿,润肤止痒。用于血燥风湿、红肿疙瘩、风湿疥癣等。 Disperses wind and dampness, moisturizes skin, and relieves itching. Indicated for blood dryness, red swollen bumps, and rheumatic scabies.
核心成分 / Active Compounds:
环戊烯基脂肪酸 (大枫子酸、海姆酸) Cyclopentenyl Fatty Acids (CPFAs: Chaulmoogric acid, Hydnocarpic acid)

01 前沿防御:接触性拒避与物理掩蔽

Advanced Defense: Contact Avoidance & Physical Masking

触觉拒食效应 [1]

Tactile Feeding Deterrence

当蚊虫接触涂抹区域时,其跗节化学感受器受到 CPFAs 刺激会引发逃避反射,显著降低刺吸尝试。

Tarsal chemoreceptors trigger avoidance reflexes upon contact with CPFAs, significantly reducing biting attempts.

气味信号掩蔽 [2]

Odor Signal Masking

高沸点植物脂质膜可阻断人体二氧化碳及乳酸散发,实现物理信号掩蔽。

The high-boiling lipid membrane blocks the emission of human volatiles (lactate/CO₂), achieving signal masking.

皮肤留存防护率对比

Comparative Protection Rate over Time

02 深度修复:叮咬后的药理干预

Deep Repair: Post-Bite Pharmacological Intervention

🧬

抗炎镇痛

Anti-inflammation & Analgesia [3]

大风子油酸可抑制组胺释放,降低局部水肿与灼热感,缓解瘙痒。

Chaulmoogric acid inhibits histamine release, reducing edema, burning sensations, and itch.

🛡️

广谱抑菌

Broad-spectrum Antibacterial [4]

具备抑菌活性,有效抑制金黄色葡萄球菌,预防抓挠引发的继发感染。

Inhibits Staphylococcus aureus, preventing secondary skin infections caused by scratching.

🧴

屏障修复

Skin Barrier Repair [5]

黄酮木脂素促进角质细胞代谢,协同基质脂肪酸修复受损物理屏障。

Flavonolignans promote keratinocyte metabolism and restore the physical skin barrier.

配伍应用与注意事项

Formulation & Usage Precautions

  • 复方协同 / Synergistic Formulation [6]可与挥发性精油(如香茅油)配伍,兼顾空间驱避与长效接触防护。
    Combines with volatile oils (e.g., Citronella Oil) to provide both spatial repellency and long-lasting contact protection.
  • ! 外用注意 / General Precaution:仅供外用,严禁口服。
    For external use only; strictly DO NOT ingest.
CPFAs 核心活性结构 Core Active Structure

环戊烯基脂肪酸是大枫子油发挥独特触觉拒避与修复功效的化学基础。
CPFAs form the chemical basis for the oil's unique repellency and healing effects.